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STUDY PROTOCOL
Year : 2016  |  Volume : 1  |  Issue : 2  |  Page : 83-84

Commentary on "femoral nerve block prevents deep venous thrombosis of the lower extremity after knee arthroplasty: a single-center randomized controlled trial"


Keck School of Medicine of University of Southern California (USC), Los Angeles, CA, USA

Correspondence Address:
Brian Wu
Keck School of Medicine of University of Southern California (USC), Los Angeles, CA
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2468-5674.183007

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Total knee arthroplasty (TKA) is the most frequently performed surgical remediation for patients with long-standing osteoarthritis, but a variety of negative outcomes following TKA have been noted, including deep vein thrombosis (DVT). It is the aim of Chen et al.'s randomized controlled trial to explore the efficacy of advanced ultra-sounded guided femoral nerve blocks for reducing serum inflammatory cytokine levels associated with DVT. By specifically measuring changes in neurtrophil elastase following use of either an advanced femoral nerve block 30 minutes prior to surgery or conventional femoral nerve block after surgery and intravenous analgesia, Chen et al.'s study will elucidate the most reliable method for preventing DVT occurrence after TKA. While this commentary identifies several limitations to the study that must be addressed, the sound study design, adequate number of participants and the potential impact of the work on improving patient outcomes from a common procedure make it a valuable contribution to the field of orthopedics. With conclusive results from this study, as well as additional studies investigating the benefits of advanced femoral nerve blocks on outcomes like muscle atrophy, the procedure could become an important consideration during TKA surgery.


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