Clinical Trials in Orthopedic Disorders

RESEARCH ARTICLE
Year
: 2018  |  Volume : 3  |  Issue : 4  |  Page : 89--96

Efficacy of arthroscopic surgery for discoid lateral meniscus injury in knee joint: a self-control study


Jian-Jun Mai1, Bin Xu2, Jun Tu2, Lei Wu2 
1 Department of Sports Trauma and Arthroscopy, First Affiliated Hospital of Anhui Medical University, Hefei; Department of Orthopedics, Maanshan People's Hospital, Maanshan, Anhui Province, China
2 Department of Sports Trauma and Arthroscopy, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China

Correspondence Address:
Bin Xu
Department of Sports Trauma and Arthroscopy, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province
China

Background and objectives: Discoid meniscus injury is a rare form of abnormal meniscus morphology with unknown pathogenesis. The complete disc-shaped meniscus is more prone than incomplete disc-shaped meniscus to tearing and adverse reactions such as joint degeneration and osteochondritis. Moreover, its clinical efficacy is not satisfactory. Arthroscopic meniscus surgery can enhance the stability of the meniscus and provide sufficient cushioning pressure to prevent recurrent meniscal tears. Therefore, this study will investigate the efficacy of arthroscopic surgery for discoid meniscus injury in knee joint and analyze risk factors that influence the efficacy of arthroscopic surgery. Methods: This single-center, self-control study will include 196 patients with discoid meniscus injury who will receive arthroscopic meniscus repair (Stryker) from December 2018 to December 2019 at the Department of Sports Trauma and Arthroscopy, First Affiliated Hospital of Anhui Medical University of China. This surgical procedure will include meniscus plasty and subtotal meniscectomy. After surgery, all included patients will be followed up for 6–18 months. Surgical efficacy will be evaluated by Lysholm score. Patients will be divided into an excellent-and-good group (Lysholm score ≥ 85) and a poor group (Lysholm score < 85). Results: The primary outcome measure of this study is the change in excellent-and-good rate of Lysholm score that reflects knee joint function measured at the last follow-up in patients undergoing arthroscopic meniscus surgery. Secondary outcome measures are Lysholm score; Outerbridge grade of chondral lesion; knee joint morphology by magnetic resonance images before surgery and at the last follow-up; age, sex, lesion region, and course of disease before surgery; and incidence of adverse reactions at the last follow-up. Clinical data from 115 patients with discoid meniscus injury (150 knees) who received treatment from April 2015 to September 2016 were retrospectively analyzed. Six to eighteen months of follow-up of 115 patients revealed a significant difference in Lysholm scores before surgery (65.80 ± 9.39) and at the last follow-up (89.15 ± 7.45; P < 0.05). Postoperative Lysholm scores were excellent in 32 patients, good in 61 patients, fair in 18 patients, and poor in four patients, with an excellent-and-good rate of 80.9%. Knee joint infection did not occur in any patient. There were four patients with lateral interstitial pain and two patients with lateral instability of the knee joint. Logistic regression analysis revealed that course of disease, age, and Outerbridge grade of chondral lesion were risk factors that influenced the efficacy of arthroscopic meniscus surgery. Conclusion: Results from this study hope to confirm that arthroscopic surgery for discoid meniscus injury is a definitive treatment technique. Patient age and the degree of chondral lesion are closely related with efficacy, so it is recommended that patients with symptomatic discoid meniscus injury undergo surgery as soon as possible. Ethics and trial registration: This study was approved by the Medical Ethics Committee, First Affiliated Hospital of Anhui Medical University (approval No. PJ2018-02-03) on February 5, 2018. The version of the study protocol is 1.0. Patients and their family members will volunteer to participate in this study. Written informed consent will be obtained from each patient. This study was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR1800019182) on October 30, 2018.


How to cite this article:
Mai JJ, Xu B, Tu J, Wu L. Efficacy of arthroscopic surgery for discoid lateral meniscus injury in knee joint: a self-control study.Clin Trials Orthop Disord 2018;3:89-96


How to cite this URL:
Mai JJ, Xu B, Tu J, Wu L. Efficacy of arthroscopic surgery for discoid lateral meniscus injury in knee joint: a self-control study. Clin Trials Orthop Disord [serial online] 2018 [cited 2019 Aug 22 ];3:89-96
Available from: http://www.clinicalto.com/article.asp?issn=2542-4157;year=2018;volume=3;issue=4;spage=89;epage=96;aulast=Mai;type=0